SELECTED PUBLICATIONS

PharmaDigest: Taking The ‘High’ Road

A Novel Approach To Treat Overactive Bladder By Positive Modulation of The GABA-B Receptor (GABA-BR) With ADX71441 (https://www.auajournals.org/doi/pdf/10.1016/j.juro.2012.02.325)
Development of Novel Metabotropic Glutamate Receptor 7 (mGluR7) Negative Allosteric Modulators for Treatment of Anxiety Disorders (Current Neuropharmacology 9:21-21 · September 2011)
The role of sodium channels in neuropathic pain (https://www.sciencedirect.com/science/article/abs/pii/S108495210600111X?via%3Dihub)
The synthesis of novel heterocyclic substituted a-amino acids; further exploitation of a-amino acid alkynyl ketones as reactive substrates (2000) (https://pubs.rsc.org/en/content/articlelanding/2000/P1/b001825m#!divAbstract)

Comparative characterization of ADX71653 and ADX71943, novel CNS- and peripherally-targeted GABAB receptor positive allosteric modulators (28th CINP World Congress of Neuropsychopharmacology, Stockholm, Sweden, 2012)
Development of novel metabotropic glutamate receptor 7 (mGluR7) negative allosteric modulators for treatment of anxiety disorders (7th International Meeting on Metabotropic Glutamate Receptors, Taormina, Italy 2011)
State-Dependent Inhibitors of the Nav1.3 Sodium Channel For Treating Neuropathic Pain (2007) (http://www.xention.com/wp-content/uploads/2007-2nd-International-Congress-on-Neuropathic-Pain-Berlin.pdf)
Targeting the Nav1.3 Sodium Channel in the Development of Novel Treatments for Neuropathic Pain (2005) (http://www.xention.com/wp-content/uploads/2005-British-Pharmacological-Society-London-.pdf)

Novel 2-amino-4,5,6,8-tetrahydropyrazolo[3,4-b]thiazolo[4,5-d]azepine derivatives and their use as allosteric modulators of metabotropic glutamate receptors (US20140349994)
Allosteric modulators of metabotropic glutamate receptors(WO2013/060029)
Novel 2-amino-4-pyrazolyl-thiazole derivatives and their use as allosteric modulators of metabotropic glutamate receptors (WO/2012/009009)
Novel tetrahydropyrazolo[3,4-b]azepine derivatives and their use as allosteric modulators of metabotropic glutamate receptors (WO/2012/009001)
Novel 2-amino-4,5,6,8- tetrahydropyrazolo[3,4-b]thiazolo[4,5-d]azepine derivatives and their use as allosteric modulators of metabotropic glutamate receptors (WO/2013/107862)
Novel fused pyrazole derivatives and their use as allosteric modulators of metabotropic glutamate receptors (WO/2012/009000)